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Key Takeaways Injectable GLP-1 medications like Mounjaro demonstrate proven weight loss of 15-20%, while patches lack scientific evidence of effectiveness

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But at the doses used, the net effect on blood sugar is positive because the GLP-1 and GIP activity dominates, and the glucagon activation primarily drives fat burning rather than glucose release

By staying hydrated, increasing your fiber intake, and utilizing supplements or laxatives when necessary, you can alleviate this common side effect

Semaglutide, manufactured by Danish company Novo Nordisk and marketed in the UK as Wegovy, is injected weekly and must be prescribed by a specialist

Chen QY, Khil J, Keum N