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New users of GLP-1RAs were matched based on age, demographics, comorbidities and medication use by using 1:1 propensity matching with other glucose-lowering drugs

They work by inhibiting glucagon secretion, delaying gastric emptying, and suppressing appetite, which helps regulate blood sugar levels and promote weight loss.However, concerns have been raised in recent years over whether these medications reduce weight mainly via muscle mass loss, which could lead to physical frailty or sarcopenia.Led by assistant professor

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