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79 ER protein 46, a new member of the thioredoxin family, highly expressed in pancreatic -cells, may mediate GLP-1 regulation of ER stress and thus increase the protection of pancreatic cells

However, its usefulness for progressed DKD and established CVD remains unclear

It shows theres potential to use these drugs in a more targeted way with patients who are planning a pregnancy and have these different comorbidities and obesity. While the findings suggest that using GLP-1 drugs before pregnancy may be beneficial in women with metabolic risk factors, having a plan to stop the medications before conception is essential, Dr

doi: 10.1016/S2213-8587(14)70120-2

[DOI] [PMC free article] [PubMed] [Google Scholar] 121.Li W., Liang X., Sun N., Zhang D

Brown, S