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1 In the 1980s, Habener was working at Massachusetts General Hospital (MGH) and studying hormones, including glucagon, which increases blood glucose, in type 2 diabetes

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A 7.6 percentage point gap in responder rate, with statistical superiority rather than just non-inferiority, is a meaningfully different result than comparable to existing options its evidence the new formulation may genuinely outperform one of the category leaders, not just match it

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The certainty of evidence, assessed using GRADE methodology, ranged from high for colorectal cancer to moderate for liver cancer to low for pancreatic cancer, reflecting variations in trial consistency and event rates (Nahra et al., 2021

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