tirzepatide pediatric Efficacy and safety of in children and adolescents with type 2 diabetes (SURPASS-PEDS): a randomised, double-blind, placebo-controlled, phase 3 trial Big update in pediatric diabetes

doi: 10.1016/j.jacadv.2025.101740 15

Risk of miscarriage and birth defects Both semaglutide and tirzepatide have been shown to cause miscarriage and birth defects in pregnant lab animals (rats and rabbits) at doses equivalent to what is used for humans

Notice the limitation immediately

However, the effect of tirzepatide on appetite and food intake was assessed in multiple clinical trials, with results indicating a general improvement in food- and appetite-related assessments, with details provided in Table S1

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