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In SURPASS-2 (T2D), all tirzepatide doses showed superior HbA1c and weight reductions vs semaglutide 1 mg

As one of the most effective weight loss medications available, Zepbound, with its active ingredient tirzepatide, stands apart

M., et al., Healthy Weight Loss Maintenance With Exercise, GLP1 Receptor Agonist, or Both Combined Followed by One Year Without Treatment: A PostTreatment Analysis of a Randomised PlaceboControlled Trial, EClinicalMedicine 69 (2024): 102475, 10.1016/j.eclinm.2024.102475

Its also not recommended for people with a history of severe pancreatitis, active gallbladder disease, or severe gastroparesis, since the medication naturally slows stomach emptying

If you are using the correct number of units for 2.5 mg , side effects should be manageable regardless of timing

The clinical support is robust