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Some prescription pain medicines, such as opioids, may cause constipation

It also helps with any possible issues that could come up when you take these together

Summary: Researchers unmasked a slight, statistically measurable increase in the risk of developing a rare, potentially permanent blinding condition known as ischemic optic neuropathy (a sudden restriction of blood flow to the optic nerve) among patients initiating GLP-1 therapy compared to standard diabetes regimens

2024 Oct 11;15:1463313

That said, if oral delivery works for you and produces consistent results, there is no specific reason it cannot be sustained long-term

GLP-1 Injection Lawsuits Climb Eli Lilly reported Mounjaro sales had exceeded expectations by about $1 billion