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However, depending on where the semaglutide is sourced from and the quality of the compounding, results will certainly vary, he says

Tirzepatide acts as a dual GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) receptor agonist, while semaglutide targets only GLP-1 receptors

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Published July 24, 2023.
The SURMOUNT-1 trial demonstrated up to 22.5% body weight reduction with tirzepatide at the highest dose (15mg weekly), compared to semaglutide's 14.9% in STEP 1
