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The mechanism by which antagonism of the incretin system can reduce body weight remains unclear, but seems like an area where understanding would be valuable

These nutrients help prevent common issues such as fatigue, muscle loss, and nutrient deficiencies that can occur when appetite is suppressed

Because it works in several areas of the body at once, it can have multiple helpful effects

Reflecting a growing acceptance of obesity as a legitimate medical condition, at least in the United State, a 2024 employer health benefits survey found that 61% of respondents support expanding Medicare (federal health insurance program primarily for individuals aged 65 and older) coverage beyond treatment for T2DM to include GLP-1 therapies for weight management in overweight individuals (Kaiser Family, F, 2024)

Maintain gradual weight loss: Whilst GLP-1 medications can facilitate rapid weight loss, a more gradual approach (around 0.51 kg per week) may better preserve muscle mass