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Findings from human islets and an in vivo T2D model suggest that these compounds may have the potential to improve T2D treatment

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They were transiently transfected with truncated GLP-2 receptors attached to LgBiT and G-SmBiT (or G-HiBiT) in a ratio of 1:1 using Lipofectamine 2000 transfection reagent (Invitrogen) and incubated for 24 h

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Current research is examining whether GLP-1 therapy can modify the trajectory of autoimmune diseases by addressing the metabolic dysfunction that amplifies immune dysregulation

Andersen, A., Lund, A., Knop, F