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How investigative journalist Gary Taubes learned to spot bad science in nutrition, why that matters for your health decisions, and how to think more like a careful scientist yourself.

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In the SURPASS-4 trial, patients receiving tirzepatide experienced an average weight loss of 7.1 kg (15.7 lbs) after 52 weeks, compared to 2.5 kg (5.5 lbs) in the insulin glargine group[6]. The SURMOUNT-1 trial tested the ability of tirzepatide to produce weight loss in people with obesity who do not have diabetes

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Three major reviews commissioned by the World Health Organization find that GLP-1 drugs including tirzepatide (sold as Mounjaro and Zepbound), semaglutide (Ozempic and Wegovy), and liraglutide (Victoza and Saxenda) can lead to substantial weight loss in people with obesity