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Both compounds are synthetic analogs of endogenous cortisol but differ in their molecular structure and in their pharmacokinetic profile

Burping or reflux has been observed, often when people eat large or fatty meals

[DOI] [PMC free article] [PubMed] [Google Scholar] 28.Leon R.M., Borner T., Reiner D.J., Stein L.M., Lhamo R., De Jonghe B.C., Hayes M.R

Liraglutide received NICE approval for weight management (TA664) in 2020, but the criteria are quite narrow

Potency and PK anchors: Lau 2015 (cAMP EC50 6.2 pmol/L), Boianelli 2024 (free fraction 0.36%), FDA 2021 (weight-change EC50 54.6 nmol/L)

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