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GLP-1 medications like semaglutide have transformed weight loss outcomes for millions, but pregnancy changes the safety equation entirely

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However, the impact on fibrosis improvement was less consistent, with no significant differences observed between semaglutide and placebo in some trials

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Reduced protein intake, a common consequence of appetite suppression, particularly in older adults or those with low baseline muscle mass, further predisposes to loss of lean tissue [30]