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As rheumatologists, we must factor this weight-efficacy relationship into our analysis of treatment responses, potentially adjusting our strategies for patients with higher body weights

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Into this already complex picture has entered a third M: Mounjaro Studies estimate that 1 in 3 women are now using mounjaro and other GLP-1 weight loss medications - such as Ozempic and Wegovy

Semaglutide has also demonstrated impressive results, with 59% NASH resolution in a phase 2 trial and substantial reductions in hepatic fat content measured by MRI

Before we go further, one important clarification: We do not prescribe phentermine at our clinic

Some people may do well with brief interventions, for example, while others may need more intense behavioral treatments, medication, or both, says Leggio