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OXM was shown to increase cAMP production in Baby Hamster Kidney (BHK) cells transfected with rodent GLP-1R and GCGR, suggesting meaningful signalling through both receptors but was less potent than Exendin-4 at the GLP-1R (34)

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New England Journal of Medicine, 384 (11), 9891002

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GLP-1RAs have been shown to protect the heart from oxidative stress and reduce the expression of pro-inflammatory cytokines (interleukin (IL)-1, TNF-, IL-6, and monocyte chemoattractant protein-1 (MCP-1)) in the myocardium