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A number of studies report frequent collections of B cells (diffuse distribution, more focal aggregates or even follicle-like structures) in up to 40% of MS patients at various stages of disease (Jain and Yong, 2021)
doi: 10.1080/14712598.2018.1473371 (6) Camerini R, Garaci E
J., Gianello, R., Pitt, S., & Roupas, P
Long-Term Safety Considerations While 24-week human trials provide reassurance about short-to-medium term safety, very long-term data (multi-year continuous use) is limited
Vukojevic et al., 2018)
