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Dec 22, 2025, 18:03 ET Average weight loss of ~17% if all patients stayed on treatment * with Wegovy (semaglutide) tablets 25 mg (~14% regardless of if patients stayed on treatment ** ) in the OASIS 4 trial 1 1.5 mg starting dose available in early January for $149 per month with savings offers

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Researchers are increasingly developing therapies that target multiple biological systems involved in hunger, metabolism, insulin regulation, and energy expenditure

Clinical research shows semaglutide produces average weight loss of approximately 15% at 12 months, while tirzepatide demonstrates even more dramatic results with up to 20% average weight loss in the same timeframe