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Additionally, the cardiac magnetic resonance substudy of the SUMMIT trial revealed that compared with placebo, tirzepatide treatment of obese HFpEF patients reduced the LV mass and paracardial adipose tissue volume, with the changes in the LV mass paralleling the degree of weight loss [166]

We examined temporal trends in annual initiation prevalence

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These medications appear to fundamentally alter how the brain processes reward signals, affecting everything from food cravings to substance use patterns