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Now layer the sex research on top

3.6 Endocrine effects The combination of GLP-1 receptor agonists and metformin has not been associated with an increase in the rate or severity of clinically relevant hypoglycemic events [32, 34, 45, 46, 115-122]

The question is why you have not started yet

Earlier-generation incretin research tools acted on the GLP-1 receptor alone, and later work introduced dual GLP-1/GIP agonism
doi: 10.1056/nejmoa2511774

At 25%, the gap widened further: 28% versus 8%
