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5.4 GIP and GLP-1 effects on lipid and glucose metabolism in adipose tissue and liver Fat and liver are two organs that play key roles in lipid and glucose metabolism, working together in concert and complimentarily to maintain lipid and glucose homeostasis

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There was an overall stroke risk reduction of 17% with GLP-1 RAs across the trials ( p = 0.0002) [13], with significant reductions in the risk of both stroke overall and ischaemic stroke (both 17%) [14]

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Another study identified isolated species, including Enterococcus faecalis , Clostridium perfringens , Clostridium bifermentans , and Clostridium butyricum , which exhibited GLP-1 inhibitory activity in the human cell line NCI-H716 74