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-1 Incretins have an important role in glucose homeostasis, regulation of appetite, energy expenditure and immunity

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Nevertheless, the overall drug exposure was not considered clinically significant

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Emgality (galcanezumab) is an injectable used to prevent migraines and treat cluster headaches

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Thus, the SELECT trial exceeded expectations (many commentators predicted the topline reduction to be likely sub-20%), but also underlined the need for further outcomes trials to clarify other potential benefits, as well as, for competitors, meeting or exceeding the performance of Wegovy

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