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The SURMOUNT-1 trial showed tirzepatide at its highest dose produced 22.5% weight loss over 72 weeks

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doi:10.1111/j.2040-1124.2010.00022.x 28

Baeyens L, De Breuck S, Lardon J, Mfopou JK, Rooman I, Bouwens L (2005) In vitro generation of insulin-producing beta cells from adult exocrine pancreatic cells
