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Description
aleniglipron and orforglipron) are functionally Gs-biased and recruit -arrestin poorly (which is typically involved in turning off the GLP-1 receptor's signal by promoting internalization and downregulation and mediating nausea and vomiting)

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Learn more about G protein-coupled receptors and G proteins, and then create a paper model of a GPCR

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These medications mimic a natural hormone to regulate appetite and promote fat loss