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The molecule is classified as a triple receptor agonist because it interacts with three endocrine receptors involved in metabolic regulation: the glucagon-like peptide-1 receptor (GLP-1R), the glucose-dependent insulinotropic polypeptide receptor (GIPR), and the glucagon receptor (GCGR)

GLP-1 Patent Expiry: The Next Big Pharma Race Has Begun GLP-1 agonists like semaglutide, tirzepatide, and liraglutide have reshaped the global diabetes and obesity market

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Accutane was the original brand name of the chemical compound isotretinoin

Thomas Kruse and Sren stergaard reflect on the development of the GLP-1 analogue, semaglutide, which is reshaping peptide therapeutics in type 2 diabetes, weight management, and beyond.