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His curiosity aroused, over the subsequent decades, he and other scientists identified many different effects the hormone has on the body, and how the hormone could be turned into a drug

The risk of gastrointestinal adverse events is increased with GLP-1RA therapy but these effects tend to be mild-to-moderate and transient, and are not the reason for observed weight loss

What does the FDA say about GLP-1s

Nutritional Priorities for Long-Term Weight Maintenance Post-therapy Given adherence challenges, clinicians should help individuals establish positive nutrition and other lifestyle practices before and during GLP-1 therapy, to increase success at maintaining such practices if the drug is stopped

This proactive approach ensures consistent quality, mitigates risks associated with ingredient variability or contamination, and builds a resilient supply chain adaptable to GLP-1 evolution and potential reformulation needs