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For instance, the American Society of Anesthesiologists has found that low blood pressure during surgery can increase the risk of postoperative delirium

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Obesity patients face plan limits, prior authorization requirements, step edits, and non-formulary coverage resulting in a staggering 40% rejection rate and a 48% loss in demand

The December 2025 Phase 3 TRIUMPH-4 results were even more impressive, with the 12mg group losing an average of 28.7% of body weight over 68 weeks