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by Annette Pinder Medications known as GLP-1 receptor agonistssuch as semaglutide and tirzepatidehave rapidly transformed the treatment of type 2 diabetes and obesity

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Task force members report early experience across three distinct cases of locally advanced CRC in patients with severe obesity, demonstrating successful preoperative visceral fat reduction through multidisciplinary coordination incorporating metabolic bariatric surgery or pharmacologic therapy during neoadjuvant windows, followed by definitive oncologic resection