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All publications available within PubMed, Google Scholar, and Cochrane databases were reviewed for peer-reviewed journal articles, clinical trial data, and evidence-based reviews

Statistical comparisons were conducted using chi-square test for categorical variables and t -test for normally distributed continuous variables or Wilcoxon rank-sum test for non-normal distributed continuous variables

Several tests, including the mixed meal test (MMT) and the modified oral glucose tolerance test (OGTT), are available to confirm this diagnosis [2,3]

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Its pathogenesis involves a dysfunctional immune response whereby the immune system erroneously attacks synovial tissue[17]
