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These molecules offer improved patient convenience, reduced injection dependency, and the ability to combine with other therapies

Oral GLP-1 currently represented by Rybelsus (oral semaglutide 7mg/14mg daily) for T2DM and advanced by Eli Lilly's orforglipron in late-stage trials is growing at the fastest route of administration CAGR because it fundamentally removes the injection barrier that constrains GLP-1 therapy adoption in the substantial patient population for whom daily or weekly self-injection is a genuine disincentive to treatment initiation or maintenance

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Those receptor systems are GIP, GLP-1, and glucagon receptors

Advances in Medicine, 2023, 9946924