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Abstract Background: Tirzepatide, a dual glucose-dependent insulinotropic polypeptide, (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist, has emerged as an effective therapy for obesity and type 2 diabetes mellitus (T2DM)
This review examines the dual mechanism of tirzepatide, its broader metabolic effects, and the critical role of pharmacists in optimizing its use
It works by improving fat metabolism, increasing insulin sensitivity, and providing significantly greater weight loss compared to single-agonist peptides such as semaglutide (Ozempic and Wegovy), liraglutide, and dulaglutide
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The secretory function of adipocytes in the physiology of white adipose tissue
