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The in vivo effects of AT-7687 were evaluated in obese cynomolgus monkeys, and when combined with the GLP-1 analogue liraglutide, AT-7687 enhances weight reduction induced by liraglutide and improves glycemic control and lipid metabolism (51)

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We do not expect any short term impact on premiums from this proposal, and in fact, this proposal provides a significant savings for people who currently may be paying out of pocket for these medications, said CMS Deputy Administrator and Director for the Center for Medicare Meena Seshamani, M.D

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