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Despite their different mechanisms, evidence does not support better weight loss outcomes when phentermine and semaglutide are combined compared to optimized monotherapy or newer dual-peptide approaches

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This amount of weight reduction dramatically exceeded the weight reduction achieved by any previous medication approved for chronic weight management [2]

[DOI] [PMC free article] [PubMed] [Google Scholar] 12.Ramos-Lobo AM, Donato J

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