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said at Thursdays announcement

Worried about GLP-1 side effects like nausea or fatigue

Recent studies have demonstrated that switching from DPP4-inhibitor to oral semaglutide helps achieve HbA1c targets with less use of additional glucose-lowering medication and offers the potential for a greater reduction in BW, despite a slight risk of gastrointestinal symptoms [30, 31]

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Moreover, while effective for some, biologics often fail to achieve sustained disease control and are associated with significant costs, potential side effects, and limited accessibility in some regions [6]

For full background on the compound, the complete retatrutide guide is a good starting point