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Grounded in protocol

Sterne JAC, Savovi J, Page MJ, Elbers RG, Blencowe NS, Boutron I, et al

However, its side effects can differ slightly: Gastrointestinal Discomfort: Nausea, bloating, and stomach pain are common, especially in the first few weeks

Monthly assessment during dose escalation determines whether to proceed, pause, or reduce doses

At week 36, a total of 670 participants were randomized (1:1) to continue receiving tirzepatide (n = 335) or switch to placebo (n = 335) for 52 weeks
