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Neuroprotection of Exendin-4 by enhanced autophagy in a Parkinsonian Rat Model of alpha-Synucleinopathy

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Excess adiposity contributes to dysregulation of the hypothalamic-pituitary-gonadal axis through increased aromatization of androgens to estradiol within adipose tissue, which may suppress hypothalamic-pituitary gonadotropin signaling, along with inflammatory signaling and alterations in sex hormone-binding globulin dynamics
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