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00:01:52 So to start off, we're going to start off by just laying the foundations of inkartin biology
The decades of research on CR suggest that the reduction in cancer incidence in CR is facilitated by the reduction in glucose, insulin, and IGF-1 levels, which would otherwise stimulate cell growth and proliferation, and the reduction in oxidative stress and inflammation (49, 50)
It is a type IV immune-mediated reaction mediated by cytotoxic T cells [63]
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If further glycaemic improvement is needed after at least one week, the dose can be increased to the maximum of 1.8 mg daily
The GLP-1 pathway slows gastric emptying
