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The second developed approach, body roundness index (BRI), associates a persons shape phenotype with high-risk adiposity components and multiple health outcomes

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Results We screened 10,670 studies and ultimately identified 5 eligible studies, encompassing 719 patients

Adult-onset type 1 diabetes mellitus differs from the early onset form in terms of residual endogenous insulin secretion, comorbidities and baseline cardiorenal risk

Interestingly, glucagon-like peptide-1 receptor agonists (GLP-1RAs), used in the treatment of T2DM and obesity, are known to show pro-cognitive and neuroprotective properties, and exert modulatory effects on immune, endocrine and metabolic processes in the central nervous system