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Accordingly, better control of cardiovascular risk factors such as blood pressure (BP) in patients with T2D is required to achieve favorable cardiovascular safety goals

48,49 Heart Rate Increase GLP-1RAs are known to cause a modest, dose-dependent increase in resting heart rate

Author AB has received speakers fees from AbbVie, Galapagos, Celltrion and Pfizer

Interleukin-1 (IL-1) receptor antagonist gene polymorphism in normal weight obese syndrome: relationship to body composition and IL-1 alpha and beta plasma levels

These modifications extend their half-lives from hours to days, allowing once-daily or once-weekly dosing

Acknowledgements The authors would like to acknowledge Dr