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Description

N Engl J Med 2015

Consult a doctor right away if your symptoms worsen and are no longer manageable at home

Dr Hoe said most of her patients come with a high Body Mass Index (BMI) and are seeking weight loss primarily for health reasons

In select cases particularly patients with: Obesity High insulin resistance Very high total daily insulin requirements endocrinologists may consider off-label use with: Continuous glucose monitoring Routine ketone monitoring Strict sick-day protocols Close specialist follow-up But this is not standard therapy

In another study in healthy and obese-diabetic animal models, allulose also elicited a GLP-1 release, reduced food intake and showed positive effects on glucose tolerance (Reference Iwasaki, Sendo and Dezaki17)