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39 Using the Ala 21 of tirzepatide can perhaps sidestep this NEP 24.11 degradation to a certain extent
Trllinger, Svenja Godbersen, Shahana Sengupta, Adrian Kaufmann, Sren Krogsgaard Thomsen, Bolette Hartmann, Yi-Chun Chen, Anna E

They work by mimicking a natural hormone in your body called glucagon-like peptide-1

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[DOI] [PMC free article] [PubMed] [Google Scholar] 6.Tran M.M., Mirza F.N., Lee A.C., Goldbach H.S., Libby T.J., Wisco O.J

In a phase 2 clinical trial, CagriSema reduced HbA1c by 2.2% (p = 0.075) in comparison with semaglutide 2.4 mg alone [101]