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Description
In December, the FDA also approved Novo's Wegovy pill for weight loss

The ventral tegmental area (VTA) and nucleus accumbens (NAc), key brain areas involved in the reinforcing effects of food and alcohol abuse, contain GLP-1 receptors, indicating central mediation of GLP-1 agonists 10

Within the year following discontinuation, 19.6% restarted the same medication and 35.2% pursued an alternative obesity treatment of some kind

For someone using GLP-1 supplements, appetite suppression can sometimes create a very large calorie deficit unintentionally

The 22.5% average weight loss, with some patients achieving 25%+ reductions, offers the best chance of reaching a healthy weight range

Preclinical studies in animal models such as SpragueDawley rats, C57BL/6 mice, and Wistar rats have reported encouraging outcomes [93]
