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The high incidence and prevalence are attributed to the ageing population and poor lifestyles (Minari et al., 2023)

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They include changes in the production of constricting and relaxing factors endothelium-derived, interruption of molecular signaling, increased oxidative stress, renal injury, insulin resistance, hyperinsulinemia, sleep apnea syndrome, that make hemodynamic alterations (108, 109)

Heaematoxylin- and eosin-stained sections were scored by a histopathologist blinded to treatment allocation using the Nonalcoholic Activity Score 70 with fat scored 03, ballooning 02, and lobular inflammation 02