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The insulinotropic functions of GLP-1 are mediated through interaction with GLP-1 receptors expressed on pancreatic cells

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iScience, 27 (6), 109903

Glucagon-like peptide-1 inhibits vascular smooth muscle cell dedifferentiation through mitochondrial dynamics regulation

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Combination therapy of DPP4is and SGLT2is reduces ENaC activity in patients with DKD To investigate whether add-on therapy of DPP4is to SGLT2is reduces USE in patients with DKD, we next conducted a retrospective clinical study of hospitalized patients with diabetes, who had been treated with or without SGLT2is alone or SGLT2is + DPP4is in Kurume University Hospital since 2010 to 2022