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Im not going to second-guess myself. Wegovy belongs to a pricey class of drugs called GLP-1s (short for glucagon-like peptide-1 agonists) that have upended the treatment of obesity in recent years, offering hope to patients who have tried and failed to lose weight in myriad other ways

Most diarrhea episodes resolve within 24-48 hours during the adjustment period

It requires energy and resources so when calorie intake drops significantly as it does during weight loss

Berberine may interact with diabetes medications, particularly increasing hypoglycaemia risk when combined with insulin or sulfonylureas, and may affect the metabolism of other medicines through enzyme inhibition

Clinical trials with a focus on improvement in fibrosis must similarly require no worsening in NASH

The emergence of GLP-1 receptor agonists, such as the first clinically approved agonist, exenatide, in 2005, paved the way for the thorough exploration of these molecules [12]
