glp-1 receptor agonist for weight loss Study finds agonists target fat over muscle Is GLP-1 Safe for Weight

Both GIP and GLP-1 receptors are found in areas of the human brain important for appetite regulation

Further, GLP-1RAs play a neuroprotective effect by stimulating the differentiation of nerve cells and inhibiting neuroinflammation (8), while they were also reported to inhibit liver inflammation (9)

Among the differentially expressed genes, 58 modules were identified as closely associated with microglial GLP-1R pathways and features of nerve injury, including pain hypersensitivity, ligation, paw withdrawal latency, and anxiety-related behaviors [64]

Potcovaru CG, Filip PV, Neagu OM, Diaconu LS, Salmen T, Cintez D, et al

Skinny shot

Unfortunately, the current trend is completely the opposite, with a steady increase in overweight and obesity affecting the youngest, putting them at very high risk of developing a veritable epidemic of cardiometabolic diseases in a few years (see our article on this subject)