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By activating all three receptors, retatrutide is designed to suppress appetite, and preclinical and early-phase data suggest it may also increase energy expenditure and improve metabolic function though robust long-term human evidence for the energy expenditure effect remains limited

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[DOI] [PubMed] [Google Scholar] 9.Lavelle A., Sokol H
The study also found that cardiometabolic risks, including dyslipidemia and hypertension, rose more rapidly in the younger population

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Its a small number, but its notable, he said
