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Brenna et al., 2016)

12 Besides setmelanotide, which is indicated for patients with rare genetic forms of obesity, these alternative anti-obesity medications result in modest weight loss, typically ranging from 3 to 9% of baseline body weight

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Furthermore, when transitioned to metformin maintenance post-discontinuation, some patients exhibit limited weight regain and maintain lower body weight and hepatic fat levels compared to baseline (123)

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