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Follow the date and storage instructions on your specific vial, and discard it if it is cloudy, discolored, or has been frozen

Lancet Public Health 7, e105e125

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While injectable GLP-1 receptor agonists such as semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) have transformed the treatment landscape for obesity and type 2 diabetes, their reliance on subcutaneous injection remains a significant barrier to broader adoption

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While neural circuits involved in food-seeking behavior and satiety are known, Zhenggang Zhu, PhD, a postdoctoral researcher at UCSD, and colleagues investigated how the ventral tegmental area (VTA) dopamine neurons regulate the consumption of pleasurable foods using cell specific circuit mapping, optogenetics, and in vivo imaging