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Most butyrate synthesized in the gut is utilized by colonocytes, with only 112 M reaching systemic circulation (Stevens and Hume, 1998)

PubMed Central, Chedid, V., et al

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2018;8(1) doi: 10.1038/s41598-018-36210-9

Data suggest Tirzepatide may help retain more lean mass during weight loss compared to Semaglutide, making it attractive for those aiming to cut fat without sacrificing muscle