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Description
Mechanism of Action Exogenous GLP-1 RA have been more recently considered as a good choice for treating patients with diabetes it works by incretin effect [1] intestinal component accounts for 50%- 70% of the total insulin secreted after an oral glucose load [2]
Because, as we discussed, diabetes itself is a known risk factor for NAION and other vision problems

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2023;388:e22
The variation in nausea rates between different GLP-1 receptor agonists relates to several pharmacological and pharmacokinetic factors

Science 261:466469 Keller J, Beglinger C, Holst JJ, Andresen V, Layer P (2009) Mechanisms of gastric emptying disturbances in chronic and acute inflammation of the distal gastrointestinal tract
